EFFECT OF SILICA IN CALCIUM PHOSPHATE MATERIAL FOR BIOMEDICAL APPLICATION

被引:0
作者
Bashah, Nor Shahida Kader [1 ]
Sahid, Sudirman [1 ]
Sabudin, Salina [1 ]
Ibrahim, Shirin [1 ]
机构
[1] Adv Mat Res Ctr AMREC, SIRIM Berhad, Biomed Mat Sect, Lot 34,Jalan Hi-Tech 2-3,Kulim Hi-Tech Pk, Kulim 09000, Kedah Darul Ama, Malaysia
来源
JURNAL TEKNOLOGI | 2015年 / 77卷 / 25期
关键词
Biphasic calcium phosphate; hydroxyapatite; tri; calcium phosphate; silica; degradation;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Calcium phosphate bioceramic materials has been widely used in medical field due to their compounds which have similarities with natural bone and teeth. Despite of these materials, silica was introduced in order to improve bioactivity level of the material. In this paper, biphasic calcium phosphate (BCP) was synthesized using calcium hydroxide (Ca(OH)(2)) and orthophosphoric acid (H3PO4) as chemical precursors at Ca/P ratio 1.60 via wet chemical technique. Additionally silicon dioxide (SiO2) at 3 and 5 wt% was added into the mixture before proceeding with spray drying process. Apatite powder obtained after spray drying process was pressed into discs and sintered at 950 degrees C to obtain biphasic mixture. Sintered Si-BCP discs were immersed in simulated body fluid (SBF) for predetermined time. Scanning Electron Microscope (SEM) images revealed that dissolution and precipitation of Si-BCP with 5% Si content occurred at day 3, while BCP without Si addition started at day 21. Formation of apatite crystal was observed on the surface of the samples. Due to this, Si-BCP has potential to be developed for quick healing medical application.
引用
收藏
页码:177 / 181
页数:5
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