RADIOIMMUNOASSAY FOR THROMBOXANE B-2

被引:183
作者
GRANSTROM, E [1 ]
KINDAHL, H [1 ]
SAMUELSSON, B [1 ]
机构
[1] KAROLINSKA INST, DEPT CHEM, S-10401 STOCKHOLM 60, SWEDEN
关键词
D O I
10.1080/00032717608059125
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A radioimmunoassay for a prostaglandin endoperoxide metabolite, thromboxane B2, was developed. The antibodies were very specific for this compound, and the method had a sensitivity of 10 pg. Platelets from a human subject were aggregated by addition of collagen and the synthesis of prostaglandin endoperoxides with time was monitored by parallel assay of prostaglandin E2, F2.alpha. and thromboxane B2.
引用
收藏
页码:611 / 627
页数:17
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