ANALGESIC ACTIVITY OF CASSIA-ALATA LEAF EXTRACT AND KAEMPFEROL 3-O-SOPHOROSIDE

被引:57
作者
PALANICHAMY, S
NAGARAJAN, S
机构
[1] BHARATHIDASAN UNIV, DEPT CHEM, Tiruchirappalli 620024, INDIA
[2] THANJAVUR MED COLL & HOSP, DEPT PHARMACOL, THANJAVUR 613004, INDIA
关键词
D O I
10.1016/0378-8741(90)90099-F
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The analgesic activity of an extract of the leaves of Cassia alata and kaempferol 3-O-sophoroside were studied after intraperitoneal injection in mice and rats using the tail clip, tail flick, tail immersion and acetic acidinduced writhing methods and the results compared with morphine. Maximum analgesic activity of the extract was apparent 120 min after injection. Fifty milligrams of kaempferol 3-O-sophoroside appeared equivalent to 100 mg of the extract. © 1990.
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页码:73 / 78
页数:6
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