SYNTHESIS OF METHYL 5-HYDROXY-2METHYL-3-OXO-1-CYCLOPENTENE-1-CARBOXYLATE - METHYL ESTER OF A PICROTOXININ DEGRADATION PRODUCT

被引：9

作者：

FINCH, N

SCHLITTLER, E

机构：

[1] Chemical Research Division, CIBA Pharmaceutical Company, Division of CIBA Corporation, Summit, NJ

来源：

TETRAHEDRON | 1968年 / 24卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(01)96336-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The known methyl 2-methyl-3-oxo-1-cyclopentene carboxylate was acetoxylated by reaction with N-bromosuccinimide and subsequent treatment with silver acetate. Methanolysis of this acetoxy compound yielded methyl 5-hydroxy-2-methyl-3-oxo-1-cyclopentene carboxylate. Reaction of silver 3,5-dinitrobenzoate with the intermediate bromo compound yielded the corresponding 3,5-dinitrobenzoate, which was identical with that derived from a picrotoxinin degradation product. © 1968.

引用

页码：5421 / +

页数：1

共 16 条

[1] REACTION OF ACETYLENIC ESTERS WITH CYANOACETIC ESTER AND PYRIDINE [J].