ENZYMATIC-SYNTHESIS OF (+)CATECHIN-ALPHA-GLUCOSIDE AND ITS EFFECT ON TYROSINASE ACTIVITY

被引：40

作者：

FUNAYAMA, M

NISHINO, T

HIROTA, A

MURAO, S

TAKENISHI, S

NAKANO, H

机构：

[1] UNIV SHIZUOKA, SCH FOOD & NUTR SCI, DEPT FOOD SCI, SHIZUOKA 422, JAPAN

[2] KUMAMOTO INST TECHNOL, FAC ENGN, DEPT APPL MICROBIAL TECHNOL, KUMAMOTO 860, JAPAN

[3] OSAKA MUNICIPAL TECH RES INST, JYOTO KU, OSAKA 536, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1993年 / 57卷 / 10期

关键词：

D O I：

10.1271/bbb.57.1666

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The glycosidation of (+)catechin, which has five hydroxyl groups with cyclodextrin glucanotransferase (CGTase, EC 2.4.1.19) and soluble starch has been studied. One of the transfer products was purified and its structure was determined to be (+)catechin 3'-O-alpha-D-glucopyranoside. This glucoside noncompetitively inhibited the activity of tyrosinase from mushroom, IC50 being 5.8 mM, but didn't inhibit that from mouse melanoma. In contrast, arbutin (hydroquinone-O-beta-D-glucopyranoside) inhibited both tyrosinases.

引用

页码：1666 / 1669

页数：4

共 9 条

[1]

FOO LY, 1989, PHYTOCHEMISTRY, V28, P1237, DOI 10.1016/0031-9422(89)80217-1

[2]

FUJINUMA Y, 1985, Patent No. 56912

[3]

HASHIMOTO A, 1984, JAP J DERMATOL, V94, P797

[4] SCREENING OF SUGARS INHIBITORY AGAINST SUCROSE-DEPENDENT SYNTHESIS AND ADHERENCE OF INSOLUBLE GLUCAN AND ACID PRODUCTION BY STREPTOCOCCUS-MUTANS [J].

IMAI, S ;

TAKEUCHI, K ;

SHIBATA, K ;

YOSHIKAWA, S ;

KITAHATA, S ;

OKADA, S ;

ARAYA, S ;

NISIZAWA, T .

JOURNAL OF DENTAL RESEARCH, 1984, 63 (11) :1293-1297

[5]

NAKANO H, 1992, DENPUN KAGAKU, V39, P1

[6] TANNINS AND RELATED-COMPOUNDS .11. FLAVANOL GLUCOSIDES FROM RHUBARB AND RHAPHIOLEPIS-UMBELLATA [J].

NONAKA, GI ;

EZAKI, E ;

HAYASHI, K ;

NISHIOKA, I .

PHYTOCHEMISTRY, 1983, 22 (07) :1659-1661

[7]

TOMITA K, 1990, FRAGRANCE J, V6, P72

[8] SPECIFICITY OF CRYSTALLINE SACCHAROGENIC AMYLASE OF MOULDS [J].

TSUJISAKA, Y ;

FUKUMOTO, J ;

YAMAMOTO, T .

NATURE, 1958, 181 (4611) :770-771

[9]

TSUJISAKA Y, 1960, B OSAKA MUNICIPAL TE, V28, P59

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