Erythrocyte Sedimentation Rate and C-Reactive Protein

被引：7

作者：

Calderon, Aaron J. ^{[1
,2
]}

Wener, Mark H. ^{[3
,4
,5
]}

机构：

[1] Exempla St Joseph Hosp, Internal Med Residency, 1835 Franklin St, Denver, CO 80218 USA

[2] Univ Colorado Denver, Sch Med, Aurora, CO USA

[3] Univ Washington, Dept Lab Med, Seattle, WA USA

[4] Univ Washington, Dept Med, Div Rheumatol, Seattle, WA USA

[5] Univ Washington Med Ctr, Clin Lab, Seattle, WA USA

来源：

HOSPITAL MEDICINE CLINICS | 2012年 / 1卷 / 03期

关键词：

Erythrocyte sedimentation rate; C-reactive protein; High-sensitivity CRP; Acute-phase reactant; Inflammatory biomarker; Disease activity; Response to therapy; Sepsis;

D O I：

10.1016/j.ehmc.2012.02.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The erythrocyte sedimentation rate (ESR) and the C-reactive protein (CRP) level are the most widely used tests to monitor and detect inflammatory disorders. ESR and CRP are both sensitive markers of inflammation and correlate with severity of inflammation, but are not specific to any particular illness. ESR is an indirect marker of serum acute-phase protein concentrations whereas CRP is a direct protein measurement, making it inherently more well-defined. A substantial number of ESR measurements are elevated by conditions other than inflammation, whereas this is extremely rare with CRP. Tandem ESR/CRP, though common practice, shows little evidence to support its clinical utility. © 2012 Elsevier Inc.

引用

页码：E313 / E337

页数：25

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