MOLECULAR-BASIS OF 11Q23 REARRANGEMENTS IN HEMATOPOIETIC MALIGNANT PROLIFERATIONS

被引：201
作者：
BERNARD, OA [1 ]
BERGER, R [1 ]
机构：
[1] CNRS, SDI 15954, F-15954 PARIS, FRANCE
来源：
GENES CHROMOSOMES & CANCER | 1995年 / 13卷 / 02期
关键词：
D O I：
10.1002/gcc.2870130202
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromosomal abnormalities of the IIq23 band occur frequently in various hematopoietic malignant disorders. Because numerous partner chromosomes have been previously described, it is now important to determine the number of genes involved at IIq23 and to clarify the role of the partner genes. Recent efforts in several laboratories have identified a trithorax-related gene that is involved in most of the IIq23 abnormalities. The aim of this review is to summarize the recent data concerning these IIq23 rearrangements and the understanding of their consequences. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码：75 / 85
页数：11
相关论文
共 79 条
[1]  
AKAO Y, 1992, CANCER RES, V52, P6083
[2]   ACUTE MONOCYTIC LEUKEMIA CHROMOSOME-STUDIES [J].
BERGER, R ;
BERNHEIM, A ;
SIGAUX, F ;
DANIEL, MT ;
VALENSI, F ;
FLANDRIN, G .
LEUKEMIA RESEARCH, 1982, 6 (01) :17-26
[3]  
BERNARD OA, 1994, ONCOGENE, V9, P1039
[4]   ACTIVATION OF MAMMALIAN DNA METHYLTRANSFERASE BY CLEAVAGE OF A ZN BINDING REGULATORY DOMAIN [J].
BESTOR, TH .
EMBO JOURNAL, 1992, 11 (07) :2611-2617
[5]  
BIONDI A, 1993, BLOOD, V82, P2943
[6]  
BORKHARDT A, 1994, LEUKEMIA, V8, P549
[7]  
BOWER M, 1994, LEUKEMIA, V8, P226
[8]  
BREEN TR, 1993, DEVELOPMENT, V117, P119
[9]   MOLECULAR ANALYSIS OF A T(11-14)(Q23-Q11) FROM A PATIENT WITH NULL-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA [J].
BURNETT, RC ;
ESPINOSA, R ;
SHOWS, TB ;
EDDY, RL ;
LEBEAU, MM ;
ROWLEY, JD ;
DIAZ, MO .
GENES CHROMOSOMES & CANCER, 1993, 7 (01) :38-46
[10]  
CALIGIURI MA, 1994, CANCER RES, V54, P370
12345678