POSSIBLE INTERACTION BETWEEN FLUOXETINE AND PIMOZIDE CAUSING SINUS BRADYCARDIA

被引：37

作者：

AHMED, I

DAGINCOURT, PG

MILLER, LG

SHADER, RI

机构：

[1] HAWAII STATE HOSP,SPECIAL SERV,KANEOHE,HI

[2] NEW ENGLAND MED CTR,DIV CLIN PHARMACOL,BOSTON,MA 02111

[3] TUFTS UNIV,SCH MED,DEPT PSYCHIAT,BOSTON,MA 02111

[4] TUFTS UNIV,NEW ENGLAND MED CTR,TRIPLE BOARD PROGRAM PSYCHIAT CHILD PSYCHIAT & PEDIAT,BOSTON,MA 02111

[5] TUFTS UNIV,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BOSTON,MA 02111

来源：

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE | 1993年 / 38卷 / 01期

关键词：

D O I：

10.1177/070674379303800116

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Fluoxetine has been reported to have interactions with antipsychotics and other antidepressants with symptoms of toxicity of these drugs. We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia. Careful monitoring should be done when these two drugs are prescribed at the same time, especially in the elderly and in patients with cardiac disease.

引用

页码：62 / 63

页数：2

共 8 条

[1]

BOUCHARD RH, 1989, AM J PSYCHIAT, V146, P1352

[2]

CIRAULO DA, 1990, J CLIN PSYCHOPHARM, V10, P213

[3] FLUOXETINE DRUG-DRUG INTERACTIONS .1. ANTIDEPRESSANTS AND ANTIPSYCHOTICS [J].