Life-threatening Pneumonitis Related to Docetaxel Chemotherapy

被引：3

作者：

Ang, Mei-Kim ^{[1
]}

Lim, Darren Wan Teck ^{[1
]}

Tan, Eng Huat ^{[1
]}

Ng, Quan Sing ^{[1
]}

Tan, Daniel Shao Weng ^{[1
]}

机构：

[1] Natl Canc Ctr Singapore, Div Med Oncol, Singapore, Singapore

来源：

PROCEEDINGS OF SINGAPORE HEALTHCARE | 2015年 / 24卷 / 01期

关键词：

Interstitial pneumonitis; Docetaxel; Chemotherapy; Respiratory failure;

D O I：

10.1177/201010581502400108

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Development of pulmonary infiltrates with respiratory symptoms in patients with advanced cancer presents a diagnostic challenge. We describe a case of a patient who developed progressive respiratory failure and bilateral lung infiltrates whilst receiving docetaxel chemotherapy for advanced lung cancer. After excluding other aetiologies, he was treated for docetaxel-related pneumonitis with corticosteroid therapy. Interstitial pneumonitis is a rare complication of Docetaxel chemotherapy but needs to be recognised and treated early, as it is associated with high mortality rates. We describe the presentation, differential diagnoses and possible mechanisms associated with drug-related pneumonitis.

引用

页码：54 / 58

页数：5

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