SYNTENY BETWEEN THE LOCI FOR A NOVEL FACIT-LIKE COLLAGEN LOCUS (D6S228E) AND ALPHA-1(IX) COLLAGEN (COL9A1) ON 6Q12-Q14 IN HUMANS

被引：49

作者：

YOSHIOKA, H

ZHANG, H

RAMIREZ, F

MATTEI, MG

MORADIAMELI, M

VANDERREST, M

GORDON, MK

机构：

[1] MT SINAI MED CTR,BROOKDALE CTR MOLEC BIOL,BOX 1126,1 GUSTAVE LEVY PL,NEW YORK,NY 10029

[2] OKAYAMA UNIV,SCH MED,DEPT MOLEC BIOL & BIOCHEM,OKAYAMA 700,JAPAN

[3] HOP ENFANTS LA TIMONE,INSERM,U242,F-13385 MARSEILLE,FRANCE

[4] CNRS,UPR 412,INST BIOL & CHIM PROT,F-69622 VILLEURBANNE,FRANCE

[5] TUFTS UNIV,SCH MED,DEPT ANAT & CELLULAR BIOL,BOSTON,MA 02111

来源：

GENOMICS | 1992年 / 13卷 / 03期

关键词：

D O I：

10.1016/0888-7543(92)90176-S

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A 1.8-kb cDNA encoding portion of a novel collagenous chain was isolated from a human rhabdomyosarcoma cell line by cross-hybridization using a chicken type V collagen probe. Sequence analysis suggests that this chain belongs to the recently discovered group of collagens, termed the FACIT class of macromolecules. This cDNA was used to locate the corresponding gene (D6S228E) to chromosome 6, notably at position 6q12-q14. Interestingly, within this region of human chromosome 6 resides the α1(IX) collagen gene (COL9A1), a member of the FACIT group. © 1992.

引用

页码：884 / 886

页数：3

共 7 条

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