SINGLE-BREATH NITRIC-OXIDE MEASUREMENTS IN ASTHMATIC-PATIENTS AND SMOKERS

被引：419
作者：
PERSSON, MG
ZETTERSTROM, O
AGRENIUS, V
IHRE, E
GUSTAFSSON, LE
机构：
[1] KAROLINSKA INST,DEPT PHYSIOL,S-17177 STOCKHOLM,SWEDEN
[2] KAROLINSKA INST,INST ENVIRONM SCI,S-10401 STOCKHOLM 60,SWEDEN
[3] KAROLINSKA HOSP,DEPT THORAC MED,S-10401 STOCKHOLM 60,SWEDEN
来源：
LANCET | 1994年 / 343卷 / 8890期
关键词：
D O I：
10.1016/S0140-6736(94)90935-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Exhaled nitric oxide (NO) concentrations were measured in asthmatic outpatients and in non-smoking and smoking healthy controls. In single exhalations, NO showed a peak suggestive of airway origin in both controls and asthmatic patients. The peak NO concentration was higher in asthmatic patients and lower in smokers than in non-smoking controls (p<0.05). The findings support a role for NO in the host defence response in asthma and suggest that NO measurements can discriminate between different types of lung disorders.
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页码：146 / 147
页数：2
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