ISOLATION AND STRUCTURAL-ANALYSIS OF THE 5'-FLANKING REGION OF THE GENE ENCODING THE HUMAN GLUCAGON RECEPTOR

被引：16

作者：

BUGGY, J

HULL, J

YOOWARREN, H

机构：

[1] Signal Transduction Section, Institute for Metabolic Disorders, Miles Inc., West Haven

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 208卷 / 01期

关键词：

D O I：

10.1006/bbrc.1995.1343

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The gene encoding the human glucagon receptor, including several kb of upstream sequence, was isolated from a bacteriophage lambda FIX II library constructed from human placental DNA. We report here the novel sequence of the 5' flanking region of the gene, the identification of a previously unreported intron of 5 kb, and the identification of the transcription start point of the glucagon receptor-specific transcript, which estimates the length of the first exon to be 300 bp. (C) 1995 Academic Press, Inc.

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页码：339 / 344

页数：6

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