REACTIVE CHANGE AND ATYPICAL SQUAMOUS CELLS OF UNDETERMINED SIGNIFICANCE IN PAPANICOLAOU SMEARS - A CYTOHISTOLOGIC CORRELATION

被引：60

作者：

SIDAWY, MK

TABBARA, SO

机构：

[1] Department of Pathology, The George Washington University Medical Center, Washington, District of Columbia

[2] Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1993年 / 9卷 / 04期

关键词：

CERVICOVAGINAL SMEAR; SQUAMOUS ATYPIA; INFLAMMATORY ATYPIA; BETHESDA SYSTEM; CYTOLOGIC CRITERIA;

D O I：

10.1002/dc.2840090410

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The purposes of this study were to delineate morphologic criteria for the terms reactive/reparative change (RC) and atypical squamous cells of undetermined significance (ASCUS), which were proposed by the Bethesda System, and to evaluate the impact of the new terminology on patient management. Using criteria defined in this article, 88 cervical smears originally reported as ''atypia'' were reclassified as RC (57) and ASCUS (31). Correlation with the colposcopically directed biopsies was as follows: 3/57 RC showed condyloma and 19/31 ASCUS had squamous lesions (14 condyloma, four mild, and one moderate dysplasia). The remainder of the cases had either cervicitis or no significant abnormality histologically. Using the proposed criteria, 61.3% of ASCUS correlated with positive biopsies, compared to 5.2 % of the RC cases. Our results indicate that patients with smears showing RC are significantly less likely to have a squamous lesion as compared to those showing ASCUS, and therefore may be managed more conservatively. (C) 1993 Wiley-Liss, Inc.

引用

页码：423 / 429

页数：7

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