CELL-MEMBRANES AS TARGETS FOR ANTICANCER DRUG-ACTION

被引：23
作者：
DAOUD, SS
机构：
[1] Department Pharmaceutical Sciences, Pharmacol./Toxicol. Graduate Program, Washington State University, Pullman
来源：
ANTI-CANCER DRUGS | 1992年 / 3卷 / 05期
关键词：
CELL MEMBRANES; DOXORUBICIN; ETHER LIPIDS; IMMUNOTOXINS; IONOPHORES; LIPOSOMES;
D O I：
10.1097/00001813-199210000-00001
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A variety of studies strongly hint that cell membranes can be important targets for new and existing anti-tumor drugs. Traditionally, the search for new anti-cancer agents has focused on compounds designed to act on the biosynthesis, stabiility or function of DNA; it may be timely, however, to broaden our search horizon and consider targets outside of the nucleus. Thus, the cell membrane as well as membraneous organelles may well play a key role in the future of anti-tumor drug development.
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收藏
页码：443 / 453
页数：11
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