FINE-NEEDLE ASPIRATION CYTOLOGY OF ALVEOLAR SOFT-PART SARCOMA

被引：29

作者：

SHABB, N ^{[1
]}

SNEIGE, N ^{[1
]}

FANNING, CV ^{[1
]}

DEKMEZIAN, R ^{[1
]}

机构：

[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT PATHOL,CYTOL SECT,1515 HOLCOMBE BLVD,HOUSTON,TX 77030

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1991年 / 7卷 / 03期

关键词：

FINE-NEEDLE ASPIRATION; SOFT-TISSUE TUMORS; ELECTRON MICROSCOPY;

D O I：

10.1002/dc.2840070317

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Alveolar soft-part sarcoma (ASPS) is a rare soft-tissue tumor. Few cases have between reported in the aspiration cytology literature. We discuss the fine-needle aspiration (FNA) cytologic features of ASPS in four patients. The smears were characterized by single cells and clusters of cells associated with thin-walled vasculature, resulting in a distinct pseudoalveolar pattern. The cells had abundant granular cytoplasm and large round nuceli with prominent central nucleoli. Binucleated and occasional multinucleated cells were present. Numerous stripped tumor nuclei were a consistent feature. Periodic acid-Schiff (PAS)-positive diastase-resistant granules were demonstrable within the intact and fragmented cytoplasm. Electron microscopy of aspirated material identified granules and crystals with the characteristic lattice pattern. To conclude, the FNA cytologic features of ASPS are characteristic. Confirmation by special stains and electron microscopy of FNA material is possible. The differential diagnostic considerations include renal cell carcinoma, paraganglioma, granular cell tumor, clear cell sarcoma, and epithelioid sarcoma.

引用

页码：293 / 298

页数：6

共 21 条

[1]

Teresa GM, Francisco G, Primitiva M, Et al., Fine needle aspiration cytology of soft‐tissue lesions, Acta Cytol, 30, pp. 671-678, (1986)

[2]

Michael AS, Biopsy of musculoskeletal tumors, J Bone Joint Surg [Am], 64 A, pp. 1253-1257, (1982)

[3]

Enneking WF, The issue of the biopsy (editorial), J Bone Joint Surg [Am], 64 A, pp. 1119-1120, (1982)

[4]

Mankin HJ, Lange TA, Spanier SS, The hazards of biopsy in patients with malignant primary bone and soft‐tissue tumors, J Bone Joint Surg [Am], 64 A, pp. 1121-1127, (1982)

[5]

Layfield LJ, Anders KH, Glasgow BJ, Mirra JM, Fine needle aspiration of primary soft‐tissue lesions, Arch Pathol Lab Med, 110, pp. 420-424, (1986)

[6]

Akerman M, Idvall I, Rydholm A, Cytodiagnosis of soft tissue tumors and tumor‐like conditions by means of fine needle aspiration biopsy, Arch Orthop Trauma Surg, 96, pp. 61-67, (1980)

[7]

Kissin MW, Fisher C, Webb AJ, Et al., Value of fine needle aspiration cytology in the diagnosis of soft tissue tumors: A preliminary study on the excised specimen, Br J Surg, 74, pp. 479-480, (1987)

[8]

Fletcher CD, Young AE, Fine needle aspiration cytology of soft tissue tumors “letter.”, Br J Surg, 74, (1987)

[9]

Kapila K, Chopra P, Verma K, Fine needle aspiration cytology of alveolar soft‐part sarcoma: A case report, Acta Cytol, 29, pp. 559-561, (1985)

[10]

Ordonez NG, Hickey RC, Brooks TE, Alveolar soft part sarcoma: A cytologic and immunohistochemical study, Cancer, 61, pp. 525-531, (1988)

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