AN ENANTIODIVERGENT SYNTHESIS OF FUSED BICYCLO[2.2.1]HEPTANE LACTONES VIA AN ASYMMETRIC DIELS-ALDER REACTION

被引：28

作者：

ARAI, Y ^{[1
]}

MATSUI, M ^{[1
]}

KOIZUMI, T ^{[1
]}

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,SUGITANI,TOYAMA 93001,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 04期

关键词：

D O I：

10.1039/p19900001233

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantiodivergent synthesis of the bicyclo[2.2.1]heptane lactone (2) is described, by regioselective reduction of the Diels-Alder adducts (3) and (4) with di-isobutylaluminium hydride followed by reductive elimination of the chiral auxiliary, 10-mercaptoisoborneol (9) through reaction with samarium(II) iodide.

引用

页码：1233 / 1234

页数：2

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