DIFFERENCES IN ADHERENCE TO BUCCAL EPITHELIAL-CELLS, IN PHAGOCYTOSIS AND IN KILLING BY NEUTROPHILS BETWEEN HUMAN AND NONHUMAN STRAINS OF CANDIDA-ALBICANS

被引:7
|
作者
SKOUTELIS, A
LIANOU, P
MARSELOU, O
PAPAVASSILIOU, J
BASSARIS, H
机构
[1] UNIV PATRAS, SCH MED, DEPT MED, INFECT DIS SECT, GR-26110 Patras, GREECE
[2] UNIV ATHENS, SCH MED, DEPT MICROBIOL, GR-11527 ATHENS, GREECE
[3] SCH HYG ATHENS, DEPT FUNGAL & PARASIT DIS, ATHENS, GREECE
关键词
D O I
10.1016/S0163-4453(95)92717-4
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The adherence of strains of Candida albicans to buccal epithelial cells as well as the phagocytosis of these organisms by human polymorphonuclear leucocytes (PMNL) was studied. The strains of C. albicans were obtained from patients' urine, from bird faeces and from soil. The strains of C. albicans obtained front patients and the environment displayed greater adhering ability (23.8 +/- 6.4 and 27.5 +/- 5.2 respectively) than the avian strains (14.4 +/- 2.2) (P <0.01). Strains obtained from the environment were resistant to phagocytosis (81.6 +/- 0.2 organisms ingested per 200 PMNL) and killing (8.4 +/- 2.6%) by PMNL as compared to human and avian strains (P <0.01). These observations indicate that environmental strains of C. albicans may be more virulent for human beings.
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页码:17 / 21
页数:5
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