LONG-TERM TRIAL ON THE EFFICACY OF NISOLDIPINE IN PATIENTS WITH CHRONIC HEART-FAILURE

被引：0

作者：

ENGLERT, R ^{[1
]}

BLANKE, P ^{[1
]}

SCHMITZ, H ^{[1
]}

WEISS, KH ^{[1
]}

机构：

[1] GARS INN,WUPPERTAL ELBERFELB,GERMANY

来源：

MEDIZINISCHE WELT | 1992年 / 43卷 / 06期

关键词：

NISOLDIPINE; HEART FAILURE; EXERCISE TOLERANCE; CLINICAL SYMPTOMS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a 8-week double-blind clinical study in 32 patients with chronic heart failure, the efficacy of an additional therapy with nisoldipine (5 mg/b.i.d.) was examined in comparison to placebo. In the second part of the study all patients were given 2 x 5-10 mg nisoldipine until the total duration of treatment was 24 weeks. After 8 weeks exercise-tolerance under nisoldipine had significantly improved compared with placebo. At the same time clinical symptoms improved markedly. Nisoldipine is a suitable adjunctive drug for treatment of chronic heart failure, particulary in those cases due to coronary heart disease.

引用

页码：510 / 514

页数：5