THE STRUCTURE AND ASSEMBLY OF ACTIVE CHROMATIN

被引：127
作者：
SVAREN, J
CHALKLEY, R
机构：
[1] J. Svaren and R. Chalkley are in the Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville
来源：
TRENDS IN GENETICS | 1990年 / 6卷 / 02期
关键词：
D O I：
10.1016/0168-9525(90)90074-G
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Much effort has been expanded towards understanding the details of how nucleosomes are established on newly replicated DNA. More recently it has begun to be possible to study the binding of both trans-acting factors and histones to DNA. This review is concerned with an assessment of the current status of this work. In addition, we discuss some of the questions that still need to be addressed in order to understand how trans-acting factors can establish extensive interactions with the DNA of active genes while they are excluded from inactive genes. © 1990.
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页码：52 / 56
页数：5
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