A MODIFIED ATKINS DIET FOR INTRACTABLE CHILDHOOD EPILEPSY

被引：0

作者：

Barzegar, Mohammad ^{[1
]}

Irandoust, Poupak ^{[2
]}

Ebrahimi Mameghani, Mehrangiz ^{[3
]}

机构：

[1] Tabriz Univ Med Sci, Pediat Hlth Res Ctr, Pediat Neurol, Tabriz, Iran

[2] Tabriz Univ Med Sci, Fac Med, Nutr & Diet Therapy, Tabriz, Iran

[3] Tabriz Univ Med Sci, Fac Hlth & Nutr, Nutr Epidemiol, Tabriz, Iran

来源：

IRANIAN JOURNAL OF CHILD NEUROLOGY | 2010年 / 4卷 / 03期

关键词：

Atkins diet; ketogenic diet; intractable epilepsy; children;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective The aim of the present study was to evaluate the efficacy and tolerability of a modified Atkins diet for intractable childhood epilepsy. Materials & Methods Twenty one children with medically intractable epilepsy were enrolled in the study. Inclusion criteria were at least four seizures per month and a trial of at least three anticonvulsants without becoming seizure-free. The subjects received the diet over a 6-month period. Results Three months after diet initiation, 15 patients (71.4%) remained on the diet and 12 (57.1%) had >50% seizure reduction. Eleven patients (52.4%) completed the 6-month study and 8 (38.1%) chose to remain on the diet afterward. At 6 months, 9 patients (42.8%) had >50% seizure reduction. The diet was more effective in cryptogenic epilepsy (p=0.032). Most complications were transient and successfully managed by careful follow-up and conservative strategies. Conclusion The modified Atkins diet is an effective and well-tolerated therapy for intractable childhood epilepsy.

引用

页码：15 / 20

页数：6

共 19 条

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