Photobiology of vitamin D in mushrooms and its bioavailability in humans

被引：102

作者：

Keegan, Raphael-John H. ^{[1
]}

Lu, Zhiren ^{[1
]}

Bogusz, Jaimee M. ^{[1
]}

Williams, Jennifer E. ^{[1
]}

Holick, Michael F. ^{[1
]}

机构：

[1] Boston Univ, Med Ctr, Dept Med, Sect Endocrinol Nutr & Diabetes,Vitamin D Skin &, Boston, MA 02215 USA

来源：

DERMATO-ENDOCRINOLOGY | 2013年 / 5卷 / 01期

基金：

美国国家卫生研究院;

关键词：

vitamin D; vitamin D-2; mushrooms; 25-hydroxyvitamin D; ultraviolet radiation;

D O I：

10.4161/derm.23321

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Mushrooms exposed to sunlight or UV radiation are an excellent source of dietary vitamin D-2 because they contain high concentrations of the vitamin D precursor, provitamin D-2. When mushrooms are exposed to UV radiation, provitamin D-2 is converted to previtamin D-2. Once formed, previtamin D-2 rapidly isomerizes to vitamin D-2 in a similar manner that previtamin D-3 isomerizes to vitamin D 3 in human skin. Continued exposure of mushrooms to UV radiation results in the production of lumisterol 2 and tachysterol 2. It was observed that the concentration of lumisterol 2 remained constant in white button mushrooms for up to 24 h after being produced. However, in the same mushroom tachysterol 2 concentrations rapidly declined and were undetectable after 24 h. Shiitake mushrooms not only produce vitamin D-2 but also can produce vitamin D-3 and vitamin D-4. A study of the bioavailability of vitamin D-2 in mushrooms compared with the bioavailability of vitamin D-2 or vitamin D-3 in a supplement revealed that ingestion of 2000 IUs of vitamin D-2 in mushrooms was as effective as ingesting 2000 IUs of vitamin D-2 or vitamin D-3 in a supplement in raising and maintaining blood levels of 25-hydroxyvitamin D which is a marker for a person's vitamin D status. Therefore, mushrooms are a rich source of vitamin D-2 that when consumed can increase and maintain blood levels of 25-hydroxyvitamin D in a healthy range. Ingestion of mushrooms may also provide the consumer with a source of vitamin D-3 and vitamin D-4.

引用

页码：165 / 176

页数：12

共 31 条

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