NEW SYNTHESIS OF ALIPHATIC ISOTHIOCYANATES FROM PRIMARY AMINES, CONVENIENT FOR IN-SITU USE

被引：31

作者：

BOAS, U ^{[1
]}

JAKOBSEN, MH ^{[1
]}

机构：

[1] UNIV COPENHAGEN,DEPT GEN & ORGAN CHEM,CTR MED BIOTECHNOL,HC ORSTED INST,DK-2100 COPENHAGEN,DENMARK

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 19期

关键词：

D O I：

10.1039/c39950001995

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Primary aliphatic amines react with carbon disulfide in the presence of BOP (benzotriazole-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate 1, giving the corresponding isothiocyanates in good to high yields and high purity; a number of isothiocyanates are synthesized and isolated or generated in situ and treated with a nucleophile.

引用

页码：1995 / 1996

页数：2

共 11 条

[1]

CASTRO B, 1975, TETRAHEDRON LETT, P1219

[2]

CASTRO B, 1977, SYNTHESIS-STUTTGART, P413

[3]

CASTRO B, 1976, SYNTHESIS-STUTTGART, P75

[4] The reactions of thiocarbonyl chloride Part I Reaction with aromatic primary amino-compounds [J].