A BOVINE HOMOLOG OF THE HUMAN TSPY GENE

被引：48

作者：

JAKUBICZKA, S ^{[1
]}

SCHNIEDERS, F ^{[1
]}

SCHMIDTKE, J ^{[1
]}

机构：

[1] HANNOVER MED SCH,INST HUMANGENET,KONSTANTY GUTSCHOW STR 8,D-30623 HANNOVER,GERMANY

来源：

GENOMICS | 1993年 / 17卷 / 03期

关键词：

D O I：

10.1006/geno.1993.1394

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have isolated a male-specific bovine genomic homologue of the human TSPY gene (testis-specific protein, Y-encoded). Two specific transcripts can be detected in bovine testicular RNA. The cloned sequence represents one copy of a clustered array of some 50-200 related sequences on the Y chromosome resembling the arrangement present in the human genome. The clone isolated from the bovine genome has two regions that are highly conserved between homo and bos. One stretch of DNA is homologous in 45 of 51 bp (88%), and the other stretch shares 71 of 100 bp (71%). © 1993 Academic Press, Inc.

引用

页码：732 / 735

页数：4

共 13 条

[1] A HUMAN Y-CHROMOSOMAL DNA-SEQUENCE EXPRESSED IN TESTICULAR TISSUE [J].

ARNEMANN, J ;

EPPLEN, JT ;

COOKE, HJ ;

SAUERMANN, U ;

ENGEL, W ;

SCHMIDTKE, J .

NUCLEIC ACIDS RESEARCH, 1987, 15 (21) :8713-8724

[2] CLONING AND SEQUENCE-ANALYSIS OF A HUMAN Y-CHROMOSOME-DERIVED, TESTICULAR CDNA, TSPY [J].

ARNEMANN, J ;

JAKUBICZKA, S ;

THURING, S ;

SCHMIDTKE, J .

GENOMICS, 1991, 11 (01) :108-114

[3] THE USE OF MALE-SPECIFIC CHROMOSOMAL DNA FRAGMENTS TO DETERMINE THE SEX OF BOVINE PREIMPLANTATION EMBRYOS [J].

BONDIOLI, KR ;

ELLIS, SB ;

PRYOR, JH ;

WILLIAMS, MW ;

HARPOLD, MM .

THERIOGENOLOGY, 1989, 31 (01) :95-104

[4] RATES OF DNA-SEQUENCE EVOLUTION DIFFER BETWEEN TAXONOMIC GROUPS [J].

BRITTEN, RJ .

SCIENCE, 1986, 231 (4744) :1393-1398

[5] NUCLEAR TARGETING SEQUENCES - A CONSENSUS [J].

DINGWALL, C ;

LASKEY, RA .

TRENDS IN BIOCHEMICAL SCIENCES, 1991, 16 (12) :478-481

[6] SEXING BOVINE EMBRYOS USING Y-CHROMOSOME SPECIFIC DNA PROBE [J].

LEONARD, M ;

KIRSZENBAUM, M ;

COTINOT, C ;

CHESNE, P ;

HEYMAN, Y ;

STINNAKRE, MG ;

BISHOP, C ;

DELOUIS, C ;

VAIMAN, M ;

FELLOUS, M .

THERIOGENOLOGY, 1987, 27 (01) :248-248

[7] TSPY-RELATED SEQUENCES REPRESENT A MICROHETEROGENEOUS GENE FAMILY ORGANIZED AS CONSTITUTIVE ELEMENTS IN DYZ5 TANDEM REPEAT UNITS ON THE HUMAN Y-CHROMOSOME [J].

MANZ, E ;

SCHNIEDERS, F ;

BRECHLIN, AM ;

SCHMIDTKE, J .

GENOMICS, 1993, 17 (03) :726-731

[8] SEQUENCES FROM A FAMILY OF BOVINE Y-CHROMOSOMAL REPEATS [J].

MATTHEWS, ME ;

REED, KC .

GENOMICS, 1992, 13 (04) :1267-1273

[9]

REIS A, 1990, HUM GENET, V84, P119

[10] HOW PROTEINS ENTER THE NUCLEUS [J].

SILVER, PA .

CELL, 1991, 64 (03) :489-497

← 1 2 →