MONOSOMY-3 AND ISOCHROMOSOME-8Q IN A UVEAL MELANOMA

被引：108
作者：
HORSMAN, DE
SROKA, H
ROOTMAN, J
WHITE, VA
机构：
[1] VANCOUVER GEN HOSP,DEPT PATHOL,VANCOUVER V5Z 1M9,BC,CANADA
[2] VANCOUVER GEN HOSP,DEPT OPHTHALMOL,VANCOUVER V5Z 1M9,BC,CANADA
来源：
CANCER GENETICS AND CYTOGENETICS | 1990年 / 45卷 / 02期
关键词：
D O I：
10.1016/0165-4608(90)90090-W
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromosome analysis of a locally invasive uveal melanoma revealed monosomy 3 and i(8q). Sublines with multiple copies of the i(8q) were also present. Loss of heterozygosity for genes on chromosome 3 and duplication of genes on 8q may play an important role in progression of uveal melanoma. © 1990.
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页码：249 / 253
页数：5
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