SYNTHESIS OF (-)-BACTOBOLIN FROM D-GLUCOSE AND FROM (+)-ACTINOBOLIN

被引：8
作者：
WARD, DE
GAI, YZ
KALLER, BF
机构：
[1] Department of Chemistry, University of Saskatchewan, Saskatoon
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 21期
关键词：
D O I：
10.1016/S0040-4039(00)73216-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The preparation of (-)-16 from (+)-3 constitutes a formal enantiospecific synthesis of (-)-bactobolin from D-glucose. The key transformation involves the diastereoselective addition of LiCHCl2 to 7 in the presence of CeCl3. The synthesis of (+)-3 from (+)-actinobolin sulfate is reported and illustrates the conversion of (+)-actinobolin into (-)-bactobolin.
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页码：3485 / 3488
页数：4
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