CYANOCUPRATE-MEDIATED INTRAMOLECULAR BIARYL COUPLINGS APPLIED TO AN ELLAGITANNIN - SYNTHESIS OF (+)-O-PERMETHYLTELLIMAGRANDIN-II

被引:77
作者
LIPSHUTZ, BH
LIU, ZP
KAYSER, F
机构
[1] Department of Chemistry University of California, Santa Barbara
关键词
D O I
10.1016/S0040-4039(00)77248-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Generation of an intramolecularly tethered, nonracemic diaryl cuprate followed by its oxidation with ground state oxygen at -78 degrees leads to a biaryl precursor to an ellagitannin. Subsequent attachment of the appropriate glucose unit completes the synthesis of the title compound.
引用
收藏
页码:5567 / 5570
页数:4
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