MOLECULAR-CLONING OF A HUMAN COMPLEMENTARY-DNA ENCODING AN INITIATION-FACTOR 2-ASSOCIATED PROTEIN (P(67))

被引:33
作者
LI, X [1 ]
CHANG, YH [1 ]
机构
[1] ST LOUIS UNIV,SCH MED,EA DOISY DEPT BIOCHEM & MOLEC BIOL,ST LOUIS,MO 63104
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期
关键词
TRANSLATIONAL REGULATION; INITIATION FACTOR-II; GLYCOPROTEIN; CDNA; (HUMAN);
D O I
10.1016/0167-4781(94)00227-T
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Rat p(67) is an initiation factor-2 associated protein, which plays important roles in translational regulation. A cDNA that encodes a homologue of rat p(67) was isolated from a human liver cDNA library. The encoded protein contains 478 amino acids with a calculated molecular mass of 52 891 and an isoelectric point of 5.64. The amino acid sequence is 92% identical to that of rat p(67). The corresponding mRNA has a size of similar to 2.1 kb and is present in all tested human tissues.
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页码:333 / 336
页数:4
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