DISSOCIATION OF TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) FROM ENZYME COMPLEXES YIELDS FULLY ACTIVE INHIBITOR

被引：79
|
作者：
MURPHY, G [1 ]
KOKLITIS, P [1 ]
CARNE, AF [1 ]
机构：
[1] CELLTECH LTD,SLOUGH SL1 4EN,BERKS,ENGLAND
来源：
BIOCHEMICAL JOURNAL | 1989年 / 261卷 / 03期
关键词：
D O I：
10.1042/bj2611031
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1031 / 1034
页数：4
相关论文
共 50 条
  • [41] Tissue inhibitor of metalloproteinase (TIMP)-1: The TIMPed balance of matrix metalloproteinases in the central nervous system
    Gardner, J
    Ghorpade, A
    JOURNAL OF NEUROSCIENCE RESEARCH, 2003, 74 (06) : 801 - 806
  • [42] Tissue inhibitor of metalloproteinases (TIMP)-1, -2 and -3 in human endometrium during the menstrual cycle
    Zhang, J
    Salamonsen, LA
    MOLECULAR HUMAN REPRODUCTION, 1997, 3 (09) : 735 - 741
  • [43] Localization of tissue inhibitor of metalloproteinases 1 (TIMP-1) in human colorectal adenoma and adenocarcinoma
    Holten-Andersen, MN
    Hansen, U
    Brünner, N
    Nielsen, HJ
    Illemann, M
    Nielsen, BS
    INTERNATIONAL JOURNAL OF CANCER, 2005, 113 (02) : 198 - 206
  • [44] IMMUNOHISTOCHEMICAL DEMONSTRATION OF COLLAGENASE AND TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) IN SYNOVIAL LINING CELLS OF RHEUMATOID SYNOVIUM
    OKADA, Y
    GONOJI, Y
    NAKANISHI, I
    NAGASE, H
    HAYAKAWA, T
    VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY, 1990, 59 (05) : 305 - 312
  • [45] Concentration of tissue inhibitor of metalloproteinases (TIMP)-1 protein in ovine follicular and luteal tissues.
    McIntush, EW
    Smith, MF
    BIOLOGY OF REPRODUCTION, 1997, 56 : 162 - 162
  • [46] IMMUNOLOCALIZATION OF TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) IN HUMAN-CELLS - CHARACTERIZATION AND USE OF A SPECIFIC ANTISERUM
    HEMBRY, RM
    MURPHY, G
    REYNOLDS, JJ
    JOURNAL OF CELL SCIENCE, 1985, 73 (FEB) : 105 - 119
  • [47] Tissue inhibitor of metalloproteinases-1 (TIMP-1) as tumor marker in colorectal cancer
    Nanna, Sorensen M.
    Blincko, S.
    Weerakoon, A.
    Dinsmore, E. J.
    Lally, J. P.
    Rogers, B. C.
    Christensen, I. J.
    Jensen, V
    Bruenner, N.
    Nielsen, H. J.
    Dowel, B.
    Davis, G.
    TUMOR BIOLOGY, 2006, 27 : 38 - 38
  • [48] Regulation of expression of the mouse tissue inhibitor of metalloproteinases-3 (TIMP-3) gene
    Sun, Y
    Kim, HT
    Bian, JH
    Wang, Y
    Pennie, W
    Colburn, NH
    TISSUE INHIBITORS OF METALLOPROTEINASES IN DEVELOPMENT AND DISEASE, PROCEEDINGS, 2000, : 25 - 32
  • [49] Beneficial effects of tissue inhibitor of metalloproteinases-2 (TIMP-2) on chronic dermatitis
    Miyoshi, H
    Kanekura, T
    Aoki, T
    Kanzaki, T
    JOURNAL OF DERMATOLOGY, 2005, 32 (05): : 346 - 353
  • [50] A VIRUS INDUCIBLE ELEMENT CONTAINED WITHIN AN INTRON OF THE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) GENE
    COULOMBE, B
    PONTON, A
    WILLIAMS, BRG
    SKUP, D
    JOURNAL OF INTERFERON RESEARCH, 1987, 7 (06): : 749 - 749
12345