Preclinical Alzheimer's disease

被引：1
|
作者：
Gil-Gregorio, P. [1 ]
Yubero-Pancorbo, R. [1 ]
机构：
[1] Hosp Clin San Carlos, Dept Geriatr, Memory Unit, Madrid, Spain
来源：
REVIEWS IN CLINICAL GERONTOLOGY | 2014年 / 24卷 / 02期
关键词：
Alzheimer's disease; preclinical stages; amyloidosis; neurodegeneration; cognition;
D O I：
10.1017/S095925981400001X
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Recently, diagnostic criteria for preclinical Alzheimer's disease have been proposed. These describe and define three stages of disease. Stage I is focused on asymptomatic cerebral amyloidosis. Stage II includes evidence of synaptic dysfunction and/or early degeneration. Finally, stage III of the disease is characterized by the beginning of cognitive decline.
引用
收藏
页码：117 / 121
页数：5
相关论文
共 50 条
  • [31] Loss of motor function in preclinical Alzheimer's disease
    Buchman, Aron S.
    Bennett, David A.
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2011, 11 (05) : 665 - 676
  • [32] Autonomic Cardiac Function in Preclinical Alzheimer's Disease
    Santos, Claudia Y.
    Machan, Jason T.
    Wu, Wen-Chih
    Snyder, Peter J.
    JOURNAL OF ALZHEIMERS DISEASE, 2017, 59 (03) : 1057 - 1065
  • [33] Diagnosis of preclinical Alzheimer's disease in a clinical setting
    Visser, PJ
    Verhey, FRJ
    Ponds, RWHM
    Jolles, J
    INTERNATIONAL PSYCHOGERIATRICS, 2001, 13 (04) : 411 - 423
  • [34] Clinical Diagnosis in Preclinical Stage of Alzheimer's Disease
    Fuentes, Patricio
    ARCHIVES OF MEDICAL RESEARCH, 2012, 43 (08) : 667 - 670
  • [35] Widespread distribution of tauopathy in preclinical Alzheimer's disease
    Schultz, Stephanie A.
    Gordon, Brian A.
    Mishra, Shruti
    Su, Yi
    Perrin, Richard J.
    Cairns, Nigel J.
    Morris, John C.
    Ances, Beau M.
    Benzinger, Tammie L. S.
    NEUROBIOLOGY OF AGING, 2018, 72 : 177 - 185
  • [36] Distinction between preclinical Alzheimer's disease and depression
    Visser, PJ
    Verhey, FRJ
    Ponds, RWHM
    Kester, A
    Jolles, J
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (05) : 479 - 484
  • [37] Identifying Earlier Alzheimer's Disease: Insights from the Preclinical and Prodromal Phases
    Luis Molinuevo, Jose
    Sanchez-Valle, Raquel
    Llado, Albert
    Fortea, Juan
    Bartres-Faz, David
    Rami, Lorena
    NEURODEGENERATIVE DISEASES, 2012, 10 (1-4) : 158 - 160
  • [38] A Comprehensive Review on Preclinical Alzheimer's Disease Models: Evaluating their Clinical Relevance
    Kushwaha, Virendra
    Sahu, Kantrol Kumar
    CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2025, 26 (02) : 186 - 207
  • [39] Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer's disease
    Lu, Kirsty
    Nicholas, Jennifer M.
    Weston, Philip S. J.
    Stout, Julie C.
    O'Regan, Alison M.
    James, Sarah-Naomi
    Buchanan, Sarah M.
    Lane, Christopher A.
    Parker, Thomas D.
    Keuss, Sarah E.
    Keshavan, Ashvini
    Murray-Smith, Heidi
    Cash, David M.
    Sudre, Carole H.
    Malone, Ian B.
    Coath, William
    Wong, Andrew
    Richards, Marcus
    Henley, Susie M. D.
    Fox, Nick C.
    Schott, Jonathan M.
    Crutch, Sebastian J.
    BRAIN COMMUNICATIONS, 2021, 3 (01)
  • [40] Polygenic resilience score may be sensitive to preclinical Alzheimer's disease changes
    Eissman, Jaclyn M.
    Wells, Greyson
    Khan, Omair A.
    Liu, Dandan
    Petyuk, Vladislav A.
    Gifford, Katherine A.
    Dumitrescu, Logan
    Jefferson, Angela L.
    Hohman, Timothy J.
    BIOCOMPUTING 2023, PSB 2023, 2023, : 449 - 460
12345