Preclinical Alzheimer's disease

被引:1
|
作者
Gil-Gregorio, P. [1 ]
Yubero-Pancorbo, R. [1 ]
机构
[1] Hosp Clin San Carlos, Dept Geriatr, Memory Unit, Madrid, Spain
关键词
Alzheimer's disease; preclinical stages; amyloidosis; neurodegeneration; cognition;
D O I
10.1017/S095925981400001X
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Recently, diagnostic criteria for preclinical Alzheimer's disease have been proposed. These describe and define three stages of disease. Stage I is focused on asymptomatic cerebral amyloidosis. Stage II includes evidence of synaptic dysfunction and/or early degeneration. Finally, stage III of the disease is characterized by the beginning of cognitive decline.
引用
收藏
页码:117 / 121
页数:5
相关论文
共 50 条
  • [1] Preclinical predictors of Alzheimer's disease
    Albert, MS
    BRAIN AND COGNITION, 1997, 35 (03) : 284 - 285
  • [2] Preclinical prediction of Alzheimer's disease
    Albert, MS
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S561 - S561
  • [3] Preclinical Alzheimer's disease criteria
    Fagan, Anne M.
    Vos, Stephanie J. B.
    LANCET NEUROLOGY, 2013, 12 (12): : 1134 - 1134
  • [4] Characteristics of preclinical Alzheimer's disease
    Visser, PJ
    Verhey, FRJ
    Ponds, RWHM
    Jolles, J
    INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2002, 17 (01) : 88 - 89
  • [5] Biomarkers for Preclinical Alzheimer's Disease
    Tan, Chen-Chen
    Yu, Jin-Tai
    Tan, Lan
    JOURNAL OF ALZHEIMERS DISEASE, 2014, 42 (04) : 1051 - 1069
  • [6] Preclinical Alzheimer's Disease Therapeutics
    Rafii, Michael S.
    JOURNAL OF ALZHEIMERS DISEASE, 2014, 42 : S545 - S549
  • [7] Detection of preclinical Alzheimer's disease
    Skoog, I
    NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (07): : 502 - 503
  • [8] Biomarkers in preclinical Alzheimer's disease
    Chong, Mei Sian
    Lim, Wee Shiong
    Sahadevan, Suresh
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2006, 7 (07) : 600 - 607
  • [9] Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease
    Bransby, Lisa
    Lim, Yen Ying
    Ames, David
    Fowler, Christopher
    Roberston, Joanne
    Harrington, Karra
    Snyder, Peter J.
    Villemagne, Victor L.
    Salvado, Olivier
    Masters, Colin L.
    Maruff, Paul
    JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 2019, : 591 - 600
  • [10] Preclinical memory markers of Alzheimer's disease
    Rogers, S. A.
    Miller, K. J.
    Dejong, J.
    Ercoli, L.
    Siddarth, P.
    Small, G.
    CLINICAL NEUROPSYCHOLOGIST, 2006, 20 (03) : 598 - 599