Three Cases of Gastric Antral Vascular Ectasia in Chronic Renal Failure

被引:10
作者
Iguchi, Akira [1 ]
Kazama, Junichiro James [1 ]
Komatsu, Masamichi [1 ]
Kaneko, Yoshikatsu [1 ]
Iino, Noriaki [1 ]
Goto, Shin [1 ]
Narita, Ichiei [1 ]
机构
[1] Niigata Univ, Grad Sch Med & Dent Sci, Div Clin Nephrol & Rheumatol, Niigata, Japan
关键词
Gastric antral vascular ectasia; Hemodialysis; Chronic kidney disease; Mechanical stress; Gastric motility;
D O I
10.1159/000332832
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Gastric antral vascular ectasia (GAVE) is currently recognized as an important cause of gastrointestinal bleeding. Chronic kidney disease (CKD) is associated with a high incidence of GAVE. We report 3 patients with CKD who presented with severe anemia and were diagnosed with GAVE; they were resistant to endoscopic argon plasma coagulation. However, remission of anemia and improvement in GAVE lesions were observed after the initiation of hemodialysis. The pathogenesis of GAVE remains largely unknown, but mechanical stress of the antrum could play an important role. This stress may be reduced by hemodialysis through improvement of uremia-associated gastrointestinal symptoms. Therefore, the initiation of hemodialysis might be effective for intractable GAVE in CKD patients.
引用
收藏
页码:15 / 19
页数:5
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