The use of isotretinoin in acne

被引:226
|
作者
Layton, Alison [1 ]
机构
[1] Harrogate & Dist Fdn Trust, Harrogate Fdn Trust, Dermatol, Lancaster Pk Rd, Harrogate HG3 3EP, N Yorkshire, England
关键词
acne; isotretinoin; teratogencity; relapse; European Directive;
D O I
10.4161/derm.1.3.9364
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Systemic isotretinoin remains the most efficacious treatment for severe acne as well as many cases of more moderate disease that are unresponsive to other treatment modalities. The current chapter outlines the mechanisms behind the excellent efficacy, describes how to optimize treatment, reviews the recommended guidelines for monitoring and summarizes adverse effects.
引用
收藏
页码:162 / 169
页数:8
相关论文
共 50 条
  • [1] The association between depression and isotretinoin use in acne
    Ng, CH
    Schweitzer, I
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2003, 37 (01): : 78 - 84
  • [2] Standardized laboratory monitoring with use of isotretinoin in acne
    Hansen, Timothy J.
    Lucking, SaraMarian
    Miller, Jeffrey J.
    Kirby, Joslyn S.
    Thiboutot, Diane M.
    Zaenglein, Andrea L.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 75 (02) : 323 - 328
  • [3] Isotretinoin and severe acne
    Reyt, Vincent
    ACTUALITES PHARMACEUTIQUES, 2018, 57 (578): : 15 - 19
  • [4] The use of oral antibiotics before isotretinoin therapy in patients with acne
    Nagler, Arielle R.
    Milam, Emily C.
    Orlow, Seth J.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (02) : 273 - 279
  • [5] Dermatological indications for the use of isotretinoin beyond acne
    Forbat, Emily
    Ali, Faisal R.
    Al-Niaimi, Firas
    JOURNAL OF DERMATOLOGICAL TREATMENT, 2018, 29 (07) : 698 - 705
  • [6] A systematic review of isotretinoin dosing in acne vulgaris
    Daly, Aoife U.
    Goncalves, Rui Baptista
    Lau, Eva
    Bowers, Joanne
    Hussaini, Naayema
    Charalambides, Maria
    Coumbe, Jack
    Flohr, Carsten
    Layton, Alison M.
    JEADV CLINICAL PRACTICE, 2023, 2 (03): : 432 - 449
  • [7] New Acne Therapies and Updates on Use of Spironolactone and Isotretinoin: A Narrative Review
    Jane J. Han
    Adam Faletsky
    John S. Barbieri
    Arash Mostaghimi
    Dermatology and Therapy, 2021, 11 : 79 - 91
  • [8] New Acne Therapies and Updates on Use of Spironolactone and Isotretinoin: A Narrative Review
    Han, Jane J.
    Faletsky, Adam
    Barbieri, John S.
    Mostaghimi, Arash
    DERMATOLOGY AND THERAPY, 2021, 11 (01) : 79 - 91
  • [9] Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment
    Melnik, Bodo C.
    CELLS, 2023, 12 (22)
  • [10] Concomitant use of an infrared fractional laser with low-dose isotretinoin for the treatment of acne and acne scars
    Yoon, Jong Hyun
    Park, Eun Joo
    Kwon, In Ho
    Kim, Chul Woo
    Lee, Geun Soo
    Hann, Seung Kyung
    Kim, Kwang Ho
    Kim, Kwang Joong
    JOURNAL OF DERMATOLOGICAL TREATMENT, 2014, 25 (02) : 142 - 146