The use of isotretinoin in acne

被引:233
作者
Layton, Alison [1 ]
机构
[1] Harrogate & Dist Fdn Trust, Harrogate Fdn Trust, Dermatol, Lancaster Pk Rd, Harrogate HG3 3EP, N Yorkshire, England
关键词
acne; isotretinoin; teratogencity; relapse; European Directive;
D O I
10.4161/derm.1.3.9364
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Systemic isotretinoin remains the most efficacious treatment for severe acne as well as many cases of more moderate disease that are unresponsive to other treatment modalities. The current chapter outlines the mechanisms behind the excellent efficacy, describes how to optimize treatment, reviews the recommended guidelines for monitoring and summarizes adverse effects.
引用
收藏
页码:162 / 169
页数:8
相关论文
共 62 条
[1]   RETINOIC ACID RECEPTORS AND RETINOID X-RECEPTORS - INTERACTIONS WITH ENDOGENOUS RETINOIC ACIDS [J].
ALLENBY, G ;
BOCQUEL, MT ;
SAUNDERS, M ;
KAZMER, S ;
SPECK, J ;
ROSENBERGER, M ;
LOVEY, A ;
KASTNER, P ;
GRIPPO, JF ;
CHAMBON, P ;
LEVIN, AA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (01) :30-34
[2]   A proposed set of new guidelines for routine blood tests during isotretinoin therapy for acne vulgaris [J].
Altman, RS ;
Altman, LJ ;
Altman, JS .
DERMATOLOGY, 2002, 204 (03) :232-235
[3]   Isotretinoin in dermatology [J].
Amichai, B ;
Grunwald, MH .
JOURNAL OF DERMATOLOGICAL TREATMENT, 2000, 11 (04) :219-240
[4]  
Azoulay L, 2008, J CLIN PSYCHIAT, pe1
[5]  
BERBIS P, 1991, ANN DERMATOL VENER, V118, P271
[6]  
Boer J, 1996, BRIT J DERMATOL, V135, P721
[7]   ISOTRETINOIN TREATMENT OF SEVERE ACNE IN POSTTRANSPLANT PATIENTS TAKING CYCLOSPORINE [J].
BUNKER, CB ;
RUSTIN, MHA ;
DOWD, PM .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 22 (04) :693-694
[8]   SUCCESSFUL TREATMENT OF HIDRADENITIS SUPPURATIVA AND RETROAURICULAR ACNE WITH ETRETINATE [J].
CHOW, ETY ;
MORTIMER, PS .
BRITISH JOURNAL OF DERMATOLOGY, 1992, 126 (04) :415-415
[9]  
Clark SM, 1996, BRIT J DERMATOL, V135, P20
[10]  
Clark SM, 1995, BR J DERMATOL S45, V133, P39