BIOCHEMICAL MARKERS OF BONE TURNOVER - AN UPDATE

被引：0

作者：

VANDAELE, PLA

BIRKENHAGER, JC

POLS, HAP

机构：

[1] ERASMUS UNIV ROTTERDAM,SCH MED,DEPT INTERNAL MED 3,POB 1738,3000 DR ROTTERDAM,NETHERLANDS

[2] ERASMUS UNIV ROTTERDAM,SCH MED,DEPT EPIDEMIOL & BIOSTAT,3000 DR ROTTERDAM,NETHERLANDS

来源：

NETHERLANDS JOURNAL OF MEDICINE | 1994年 / 44卷 / 02期

关键词：

BIOCHEMICAL MARKERS; OSTEOPOROSIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Currently, biomarkers are available which have considerably increased the possibility of monitoring changes in bone turnover. Assays for carboxy-terminal procollagen I fragments, osteocalcin and the bone-specific isoenzyme of alkaline phosphatase allow a more precise assessment of the complex osteoblastic functions in health and disease; osteocalcin appears at present to be the most satisfactory one. With respect to bone resorption, the measurement of urinary pyridinoline cross-links seems to be the most reliable assay. It has to be emphasisized, however, that a single biomarker may be of value in some metabolic bone diseases but not in others.

引用

页码：65 / 72

页数：8

共 60 条

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