HISTOMORPHOMETRY OF HYDROXYAPATITE-COATED AND UNCOATED POROUS TITANIUM BONE IMPLANTS

被引：106

作者：

MORONI, A ^{[1
]}

CAJA, VL ^{[1
]}

EGGER, EL ^{[1
]}

TRINCHESE, L ^{[1
]}

CHAO, EYS ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN,ORTHOPAED BIOMECH LAB,ROCHESTER,MN 55905

来源：

BIOMATERIALS | 1994年 / 15卷 / 11期

关键词：

BONE INGROWTH; HYDROXYAPATITE COATING; TITANIUM; POROUS COATING;

D O I：

10.1016/0142-9612(94)90119-8

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Two different groups of hydroxyapatite (HA) coated and uncoated porous titanium implants, 250-350 mu m and 500-700 mu m diameter beads, were press-fitted into femoral canine cancellous bone. After 12 wks, the dogs were killed and histomorphometric backscattered electron microscopy studies were carried out. Comparing HA coated Versus uncoated implants in the 250-350 mu m bead diameter group, the percentage of bone (P = 0.01) and bone index (P = 0.01) were higher in the HA coated implants. Comparing HA coated Versus uncoated implants in the 500-700 mu m bead diameter group, bone ingrowth (P = 0.01) and bone depth penetration (P = 0.008) were higher in HA coated samples. It can be concluded that the HA coating was an effective method for improving bone formation and ingrowth in the porous implants.

引用

页码：926 / 930

页数：5

共 22 条

[1]

BACHUS KN, 1988, T ORTHOP RES SOC, V13, P308

[2]

Bloebaum R D, 1990, J Biomater Appl, V5, P56

[3]

COLLIER JP, 1988, CLIN ORTHOP RELAT R, V235, P173

[4]

COOK SD, 1991, CLIN ORTHOP RELAT R, V265, P280

[5]

COOK SD, 1988, CLIN ORTHOP RELAT R, V232, P225

[6]

COOK SD, 1988, CLIN ORTHOP RELAT R, V234, P90

[7]

COOK SD, 1988, CLIN ORTHOP RELAT R, V230, P303

[8]

COVENTRY MB, 1991, JOINT REPLACEMENT AR, P491

[9]

Engh C. A., 1983, CLIN ORTHOP RELAT R, V176, P52

[10]

Galante J.O., 1985, ADV CONCEPTS TOTAL H, P135

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