COLLOIDAL THORIUM DIOXIDE (THOROTRAST) IN RADIOLOGY WITH EMPHASIS ON HEPATIC CANCEROGENESIS - A CASE REPORT OF OCCLUDED CAROTID AND JUGULAR VESSELS WITH NERVE INJURIES AND A CASE OF HEPATOMA 27 AND 33 YEARS AFTER ITS ADMINISTRATION

Two cases of severe thorotrast reaction are reported. In 1, a 60 year old male, extravasation of thorotrast had occurred into the carotid sheath 27 years previously at attempted carotid arteriography wich resulted in obliteration of the right common carotid artery and internal jugular vein. The 2nd case, a 53 year old male, developed a liver cell type of carcinoma (hepatoma) 33 years after the intravenous administration of thorotrast. The history, dosage, roentgenographic diagnosis, sequelae, and the present day use of this colloidal form of thorium dioxide are discussed.