MATERNAL AND NEONATAL RISK-FACTORS FOR CRYPTORCHIDISM

被引:94
作者
BERKOWITZ, GS
LAPINSKI, RH
GODBOLD, JH
DOLGIN, SE
HOLZMAN, IR
机构
[1] Department of Obstetrics, Department of Gynecology and Reproductive Science, Mount Sinai School of Medicine, New York, NY
[2] Department of Community Medicine, Mount Sinai School of Medicine, New York, NY
[3] Department of Surgery, Mount Sinai School of Medicine, New York, NY
[4] Department of Pediatrics, Mount Sinai School of Medicine, New York, NY
关键词
CRYPTORCHIDISM; RISK FACTORS; BIRTH-WEIGHT; GESTATIONAL AGE; COHORT STUDY;
D O I
10.1097/00001648-199503000-00007
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We assessed risk factors for cryptorchidism in a prospective hospital-based cohort study at Mount Sinai Hospital in New York City. We examined at birth 6,699 singleton male neonates who were delivered between October 1987 and October 1990. Follow-up examinations were undertaken at 3 months and 1 year for those diagnosed as cryptorchid at birth. We calculated prevalence ratios and adjusted odds ratios according to selected maternal and neonatal characteristics for those who remained cryptorchid at the 1 year assessment. We found elevated risks for maternal obesity [prevalence ratio = 2.42; 95% confidence interval (CI) = 1.11-5.27], for infants delivered by cesarean section (adjusted odds ratio = 2.17; 95% CI = 1.29-3.65), for low birthweight (adjusted odds ratio = 2.29; 95% CI = 1.12-4.70), for preterm birth (adjusted odds ratio = 2.25; 95% CI = 1.16-4.35), and for infants with congenital malformations (prevalence ratio = 13.97; 95% CI = 1.27-26.67). We observed a seasonal effect, with a peak in births of cryptorchid infants during September through November and a smaller peak during the months of March through May. We found no evidence that young women, white women, or primiparas were at increased risk.
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收藏
页码:127 / 131
页数:5
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