FACTORS DETERMINING THE PROTON T1 RELAXIVITY IN SOLUTIONS CONTAINING GD-DTPA - A REEVALUATION

被引：4
|
作者：
JACKSON, GE [1 ]
DUTOIT, LL [1 ]
机构：
[1] MRC,MED BIOPHYS RES INST,TYGERBERG 7505,SOUTH AFRICA
来源：
POLYHEDRON | 1992年 / 11卷 / 11期
关键词：
D O I：
10.1016/S0277-5387(00)83360-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The relaxation behaviour of Gd-DTPA in serum has been studied, the relaxation times of Gd3+ and [Gd(DTPA)]2- solutions being measured in the presence of serum albumin, CuCl2 and CaCl2. The results are interpreted in terms of a computer model of relaxivity in which all the possible metal-ion equilibria are included. Weak binding (K = 270 +/- 30) of [Gd(DTPA)]2- to serum albumin is postulated to occur.
引用
收藏
页码：1315 / 1318
页数：4
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