EFFECT OF CONCENTRATION ON VASOACTIVITY OF BUPIVACAINE AND LIGNOCAINE

被引：87

作者：

APS, C

REYNOLDS, F

机构：

[1] ST THOMASS HOSP & MED SCH, DEPT ANAESTHETICS, LONDON SE1, ENGLAND

[2] ST THOMASS HOSP & MED SCH, DEPT PHARMACOL, LONDON SE1, ENGLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1976年 / 48卷 / 12期

关键词：

D O I：

10.1093/bja/48.12.1171

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

In a double-blind trial bupivacaine 0.125, 0.25 and 0.5% and lignocaine 0.5, 1 and 2% were given intradermally to 31 volunteers. Vasoconstriction was observed more frequently at low concentrations of each drug and vasodilatation at high concentrations. These observations were highly significant (P < 0.001). Duration of action was unaffected by concentration, except in the case of bupivacaine 0.5%, the effect of which was longer lasting than that of other solutions.

引用

页码：1171 / 1174

页数：4

共 12 条

[1]

BERLING C, 1958, ODONTOL REVY, V9, P254

[2]

BLAIR MR, 1975, BRIT J ANAESTH, V47, P247

[3] ETIDOCAINE - CLINICAL EVALUATION FOR INTERCOSTAL NERVE BLOCK AND LUMBAR EPIDURAL BLOCK [J].