Antigenic similarity of Central European encephalitis and louping-ill viruses

被引:0
|
作者
Hubalek, Z [1 ]
Pow, I [1 ]
Reid, HW [1 ]
Hussain, MH [1 ]
机构
[1] MOREDUN RES INST,EDINBURGH EH17 7JH,MIDLOTHIAN,SCOTLAND
关键词
Flavivirus; tick-borne encephalitis virus; louping-ill virus; antigenic similarity; monoclonal antibodies; immunofluorescence assay; taxonomy; nomenclature;
D O I
暂无
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Twenty isolates of Central European encephalitis (CEE) virus were compared with 20 isolates of louping-ill (LI) virus in indirect immunofluorescence test (IIFT), using a panel of 17 monoclonal antibodies (MoAbs) prepared against the prototype LI virus. Three Asian members of the tick-borne encephalitis (TEE) complex were also included in the comparison: Turkish sheep encephalitis (TSE), Russian spring-summer encephalitis (RSSE) and Langat (LGT) viruses. Antigenic relationships of the viruses were evaluated by Dice similarity coefficient and cluster analysis. The results revealed antigenic heterogeneity of LI isolates, antigenic homogeneity of CEE isolates, and indicated that CEE and LI are related varieties of Eurasian TEE flavivirus that also includes TSE and RSSE strains.
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页码:251 / 256
页数:6
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