IMMUNOHISTOCHEMICAL STUDY OF C-ERBB-2 ONCOPROTEIN EXPRESSION IN EXTRAMAMMARY PAGETS-DISEASE

被引：16
作者：
NISHI, M [1 ]
YOSHIDA, H [1 ]
SETOYAMA, M [1 ]
TASHIRO, M [1 ]
机构：
[1] KAGOSHIMA UNIV,FAC MED,DEPT PATHOL,KAGOSHIMA,JAPAN
来源：
DERMATOLOGY | 1994年 / 188卷 / 02期
关键词：
C-ERBB-2; EXTRAMAMMARY PAGETS DISEASE; MALIGNANCY;
D O I：
10.1159/000247110
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Sections of formalin-fixed, paraffin-embedded tumor tissue from 20 patients with noninvasive extramammary Paget's disease and 2 patients with invasive extramammary Paget's disease were stained immunohistochemically by means of anti-c-erbB-2 product monoclonal antibody. Membrane staining of intraepidermal tumor cells was found in only 3 of 20 cases of noninvasive extramammary Paget's disease. In the 2 invasive cases, tumor cells of invasive lesions and metastases were positive while intraepidermal tumor cells were negative.
引用
收藏
页码：100 / 102
页数：3
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