TREATMENT AND DEVELOPMENTAL THERAPEUTICS IN ASPERGILLOSIS .1. AMPHOTERICIN-B AND ITS DERIVATIVES

被引：0
作者：
STGEORGIEV, V
机构：
来源：
RESPIRATION | 1992年 / 59卷 / 05期
关键词：
ASPERGILLOSIS; TREATMENT OF; AMPHOTERICIN-B; ESTERS OF AMPHOTERICIN-B; POLYENE ANTIBIOTICS; BENZO[A]NAPHTHACENE ANTIBIOTICS; NIKKOMYCINS; CILOFUNGIN;
D O I：
暂无
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
In recent years, the frequency of infections caused by Aspergillus sp. has been on the rise. Immunocompromised patients are especially vulnerable to such infections. The polyene antibiotic amphotericin B is currently considered to be therapeutically the most effective drug against Aspergillus-induced infections. In the present review, the clinical efficacy of amphotericin B, its toxicities and various routes of applications, are discussed. Different combinations of ampbotericin B with other drugs have also been reviewed, along with the anti-Aspergillus activity of various other antibiotics and some ester derivatives of amphotericin B.
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页码：291 / 302
页数：12
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