We evaluate retrospectively 38 patients with AIDS and Cytomegalovirus (CMV) retinitis. In 72.5% (45 from 62 eyes) it carried an important sight risk; 50% of the end of the follow-up. Evidence of extraocular illness in 28.5% of the patients. Using control groups the AIDS microvasculopathy is neither more frequent in CMV-retinitis nor associated with a special risk group (p>0.05), we review treatment, follow-up and complications. The median survival was 6 months without significans differences (p>0.05) with or without the finding of microvasculopathy, bilaterality or extraocular illness.