HOW SOON AFTER QUITTING SMOKING DOES RISK OF HEART-ATTACK DECLINE

被引：103

作者：

DOBSON, AJ ^{[1
]}

ALEXANDER, HM ^{[1
]}

HELLER, RF ^{[1
]}

LLOYD, DM ^{[1
]}

机构：

[1] ROYAL NEWCASTLE HOSP,CTR CLIN EPIDEMIOL & BIOSTAT,NEWCASTLE,NSW 2300,AUSTRALIA

来源：

JOURNAL OF CLINICAL EPIDEMIOLOGY | 1991年 / 44卷 / 11期

基金：

英国医学研究理事会;

关键词：

CASE CONTROL; CIGARETTE SMOKING; CORONARY HEART DISEASE; FIBRINOGEN; WHO MONICA PROJECT;

D O I：

10.1016/0895-4356(91)90157-5

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

A population-based case-control study (involving 1282 cases and 2068 controls) was conducted to examine the risk of myocardial infarction or coronary death after cigarette smokers quit smoking. The odds ratios for current smokers were significantly elevated compared to non-smokers (OR = 2.7 for men and OR = 4.7 for women). For ex-smokers odds ratios declined rapidly after quitting and after about 3 years they were not significantly different from unity. Fibrinogen concentrations measured in the controls only were higher in current smokers and ex-smokers up to 2 years after quitting than in non-smokers and after that time were similar to levels in non-smokers; however, most of the differences among categories of smokers were not statistically significant. These results support the hypothesis that risk of a coronary event in ex-smokers declines rapidly after quitting and within 2-3 years is similar to the risk for non-smokers.

引用

页码：1247 / 1253

页数：7

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