SOME ALDOSTERONE-PRODUCING ADRENAL-TUMORS ALSO SECRETE CORTISOL, BUT PRESENT CLINICALLY AS PRIMARY ALDOSTERONISM

被引：18

作者：

TUNNY, TJ ^{[1
]}

KLEMM, SA ^{[1
]}

GORDON, RD ^{[1
]}

机构：

[1] UNIV QUEENSLAND,GREENSLOPES HOSP,DEPT MED,ENDOCRINE HYPERTENS RES UNIT,BRISBANE,QLD 4120,AUSTRALIA

来源：

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 1990年 / 17卷 / 03期

关键词：

adrenal carcinoma; angiotensin II‐responsive aldosterone‐producing adenoma; angiotensin II‐unresponsive aldosterone‐producing adenoma; cortisol; dexamethasone; glucocorticoid‐suppressible hyperaldosteronism; idiopathic hyperaldosteronism; primary aldosteronism;

D O I：

10.1111/j.1440-1681.1990.tb01300.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. Two patients with angiotensin‐responsive aldosterone‐producing adenoma (APA) and one with adrenal cortical carcinoma demonstrated autonomous secretion of cortisol as well as of aldosterone. 2. The response of cortisol and of aldosterone to ACTH did not differentiate between the two APA which secreted cortisol and the eight which demonstrated normal suppression with dexamethasone. 3. Concurrent autonomous secretion of cortisol as well as aldosterone may occur in patients who present clinically with primary aldosteronism. 4. Biochemical distinctions between adenomas may reflect differences in their cellular composition. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：167 / 171

页数：5

共 12 条

[1] ALDOSTERONE-PRODUCING ADRENOCORTICAL CARCINOMA - PREOPERATIVE RECOGNITION AND COURSE IN 3 CASES [J].