Research Progress on Novel Carrier-modified Methods and Evaluation of Active Targeting Antitumor Preparation

被引:3
作者
Wang, Jun-jun [1 ]
Huang, Sheng-wu [1 ]
机构
[1] Zhejiang Chinese Med Univ, Hangzhou 310053, Zhejiang, Peoples R China
关键词
active targeting; antitumor; carrier-modified methods; evaluation;
D O I
10.1016/S1674-6384(14)60002-2
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This article mainly introduced novel carrier-modified methods for active targeting antitumor preparation as well as their evaluation methodology in recent years. By reviewing related domestic and overseas literatures, the up-to-date scientific researches concerning active targeting antitumor preparation were elaborated and the problems existing in present studies were discussed. Numerous valid vector-embellished methods had been discovered with excellent targeting effects, and the significant progress was acquired for the evaluation tools in vitro and in vivo. The active targeting agent would be a major direction in prospective tumor or cancer therapeutic regimen.
引用
收藏
页码:22 / 28
页数:7
相关论文
共 70 条
[51]   Synthesis, characterization, and in vitro evaluation of two synergistic anticancer drug-containing hepatoma-targeting micelles formed from amphiphilic random copolymer [J].
Wang, Jianfeng ;
Yin, Cui ;
Tang, Guping ;
Lin, Xianfu ;
Wu, Qi .
BIOMATERIALS SCIENCE, 2013, 1 (07) :774-782
[52]   The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies [J].
Wang, Jin ;
Tian, Shaomin ;
Petros, Robby A. ;
Napier, Mary E. ;
DeSimone, Joseph M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (32) :11306-11313
[53]   Preparation and physicochemical characterization of a novel paclitaxel-loaded amphiphilic aminocalixarene nanoparticle platform for anticancer chemotherapy [J].
Weeden, Clare ;
Hartlieb, Karel J. ;
Lim, Lee Yong .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2012, 64 (10) :1403-1411
[54]   Preparation of Novel Ferrocene-Based Shell Cross-Linked Thermoresponsive Hybrid Micelles with Antitumor Efficacy [J].
Wei, Hua ;
Quan, Chang-Yun ;
Chang, Cong ;
Zhang, Xian-Zheng ;
Zhuo, Ren-Xi .
JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 114 (16) :5309-5314
[55]  
[徐金军 Xu Jinjun], 2011, [中国组织工程研究与临床康复, Journal of Clinical Rehabilitative Tissue Engineering Research], V15, P9583
[56]   Preparation and Characterization of Folate-Chitosan-Gemcitabine Core-Shell Nanoparticles for Potential Tumor-Targeted Drug Delivery [J].
Xu, Shi ;
Xu, Qian ;
Zhou, Jiahua ;
Wang, Junying ;
Zhang, Niping ;
Zhang, Ling .
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2013, 13 (01) :129-138
[57]   A two-stage reverse dialysis in vitro dissolution testing method for passive targeted liposomes [J].
Xu, Xiaoming ;
Khan, Mansoor A. ;
Burgess, Diane J. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2012, 426 (1-2) :211-218
[58]  
[徐秀 Xu Xiu], 2012, [材料导报, Materials Review], V26, P88
[59]   Anticancer Drug-Loaded Nanospheres Based on Biodegradable Amphiphilic ε-Caprolactone and Carbonate Copolymers [J].
Yan, Guo-Ping ;
Zong, Rong-Feng ;
Li, Liang ;
Fu, Ting ;
Liu, Fan ;
Yu, Xiang-Hua .
PHARMACEUTICAL RESEARCH, 2010, 27 (12) :2743-2752
[60]  
Yang JM, 2012, CHIN PHARM, V21, P1