THE BIOSYNTHESIS OF CARBOCYCLIC NUCLEOSIDES

被引:28
作者
JENKINS, GN
TURNER, NJ
机构
[1] Department of Chemistry, University of Exeter, Stocker Road, Exeter EX4 4QD, United Kingdom
关键词
D O I
10.1039/cs9952400169
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Aristeromycin and neplanocin A are two naturally occurring carbocyclic nucleosides isolated from Streptomyces citricolor. They belong to a small family of cyclopentane-containing natural products that are derived from carbohydrates, in this case D-glucose, as the ultimate biosynthetic precursor. This review outlines our current understanding of the biosynthesis of aristeromycin and neplanocin and proposes possible mechanisms for the conversion of carbohydrates into 5-membered ring carbocycles.
引用
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页码:169 / 176
页数:8
相关论文
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