THE BIOSYNTHESIS OF CARBOCYCLIC NUCLEOSIDES

被引：28
|
作者：
JENKINS, GN
TURNER, NJ
机构：
[1] Department of Chemistry, University of Exeter, Stocker Road, Exeter EX4 4QD, United Kingdom
来源：
CHEMICAL SOCIETY REVIEWS | 1995年 / 24卷 / 03期
关键词：
D O I：
10.1039/cs9952400169
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aristeromycin and neplanocin A are two naturally occurring carbocyclic nucleosides isolated from Streptomyces citricolor. They belong to a small family of cyclopentane-containing natural products that are derived from carbohydrates, in this case D-glucose, as the ultimate biosynthetic precursor. This review outlines our current understanding of the biosynthesis of aristeromycin and neplanocin and proposes possible mechanisms for the conversion of carbohydrates into 5-membered ring carbocycles.
引用
收藏
页码：169 / 176
页数：8
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