MICROBIAL CONVERSION OF COMPACTIN (ML-236B) TO ML-236A

被引：14

作者：

KOMAGATA, D ^{[1
]}

YAMASHITA, H ^{[1
]}

ENDO, A ^{[1
]}

机构：

[1] TOKYO NOKO UNIV,DEPT AGR & BIOL CHEM,3-5-8 SAIWAICHO,FUCHU,TOKYO 183,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1986年 / 39卷 / 11期

关键词：

D O I：

10.7164/antibiotics.39.1574

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1574 / 1577

页数：4

共 6 条

[1] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].

ENDO, A ;

KURODA, M ;

TANZAWA, K .

FEBS LETTERS, 1976, 72 (02) :323-326

[2] MONACOLIN-J AND MONACOLIN-L NEW INHIBITORS OF CHOLESTEROL-BIOSYNTHESIS PRODUCED BY MONASCUS-RUBER [J].

ENDO, A ;

HASUMI, K ;

NEGISHI, S .

JOURNAL OF ANTIBIOTICS, 1985, 38 (03) :420-422

[3] DIHYDROMONACOLIN-L AND MONACOLIN-X, NEW METABOLITES THOSE INHIBIT CHOLESTEROL-BIOSYNTHESIS [J].

ENDO, A ;

HASUMI, K ;

NAKAMURA, T ;

KUNISHIMA, M ;

MASUDA, M .

JOURNAL OF ANTIBIOTICS, 1985, 38 (03) :321-327

[4] MONACOLIN-K, A NEW HYPOCHOLESTEROLEMIC AGENT PRODUCED BY A MONASCUS SPECIES [J].

ENDO, A .

JOURNAL OF ANTIBIOTICS, 1979, 32 (08) :852-854

[5] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM [J].

ENDO, A ;

KURODA, M ;

TSUJITA, Y .

JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348

[6] COMPACTIN (ML-236B) AND RELATED-COMPOUNDS AS POTENTIAL CHOLESTEROL-LOWERING AGENTS THAT INHIBIT HMG-COA REDUCTASE [J].

ENDO, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (04) :401-405

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