INVIVO EFFECTS OF SINGLE OR COMBINED DIETARY ANTIMUTAGENS ON MUTAGEN-INDUCED CHROMOSOMAL-ABERRATIONS

被引：48
|
作者：
RENNER, HW
机构：
[1] Federal Research Centre for Nutrition
来源：
MUTATION RESEARCH | 1990年 / 244卷 / 02期
关键词：
Antimutagens; Chlorophyllin; In vivo chromosome aberration test; Thio-tepa; α-Linolenic acid methyl ester; β-Carotene;
D O I：
10.1016/0165-7992(90)90070-Z
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The food components chlorophyllin, β-carotene and α-linolenic acid (in its methyl ester form) were tested in Chinese hamsters for antimutagenic activity on the powerful mutagen thio-tepa. Each of these natural protective compounds inhibited by 70-85% the clastogenic effects induced by the mutagen. When 2 or 3 of these antimutagens were administered simultaneously no additive effects were observed. α-Linolenic acid methyl ester was the most effective antimutagen under the experimental conditons. © 1990.
引用
收藏
页码：185 / 188
页数：4
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