Role of TGF-beta and BMP-7 Fibroeyestie Disease of Kidney

被引：0

作者：

Ogutmen, Melike Betul ^{[1
]}

机构：

[1] Mamara Univ Tip Fakultesi, Nefrol Bilim Dali, Gardenya 4 1 D 3 62 Ad3, Istanbul, Turkey

来源：

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL | 2007年 / 16卷 / 01期

关键词：

renal diseases; TGF beta; BMP-7;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The role of a multfunctional cytokin called TGF-beta in the genesis of fibrosis has been investigaed in various trails. Experimental studies showed TGF-beta production causes glomentlosclooress and tubolomestial fibroses in the rerial issue in a few works. On the constemy, fibrosis process characterises of a new cytokin called bone geophogenie protein (BMP-7) which belongs to a subgroup of the TGF-beta family is gelling may attention. The role of GMP-7 for the treatment of tubolocaterisital illinois seen in the progressive renal diseases is being started to investigate to my of hte experimental studies done recently, estigenous BMP-7 was used, at nephropathy model and successful results were reported. These exciting results are pointing our the beginning of a new era in the treatment of progressive renal diseases with fibrosis where these experimental, studies, clinically.

引用

页码：8 / 10

页数：3

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